프레비타민 D3

프레비타민 D3
IUPAC명 (3S,6Z)-9,10-세코코레스타 5(10),6,8-트리엔3-올
별칭 Precalciferol3
식별 정보
CAS 등록 번호	1173-13-3
PubChem	5281058
일화말번호	J16.363E
EINECS 번호	2146342
MeSH	previtamin+D(3)
특성
화학식	C27H44O
몰 질량	384.64 g mol－1
특기없는 경우, 데이터는 상온(25оC)・상압(100 kPa)에 있어서의 것이다.

프레비타민 D₃(프레비타민・데・쓰리)는, 비타민 D₃의 중간체인[¹][²][³][⁴].

콜레스테롤이 대사를 받아 프로 비타민 D₃(7-데히드로코레스테로르)가 된 뒤, 피부상에서 자외선을 받아 스테로이드핵의 B환이 열려, 프레비타민 D₃((6 Z)-타카르시오르)가 된다.

프레비타민 D₃는, 자발적으로 비타민 D₃(코레카르시페로르)에 이성화한다.프레비타민 D₃로부터의 비타민 D₃(코레카르시페로르)에의 전이는, 실온으로는 12일간으로 완료하는[⁵].

각주

1. ^ MacLaughlin JA, Anderson RR, Holick MF (May 1982). "Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin". Science (journal) 216 (4549): 1001□3. PMID 6281884. http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=6281884. 
2. ^ Webb AR (September 2006). "Who, what, where and when-influences on cutaneous vitamin D synthesis". Prog. Biophys. Mol. Biol. 92 (1): 17–25. doi:10.1016/j.pbiomolbio. 2006.02. 004. PMID 16766240. http://linkinghub.elsevier.com/retrieve/pii/S0079-6107(06)00020-4. 
3. ^ Pope SJ, Holick MF, Mackin S, Godar DE (2008). "Action spectrum conversion factors that change erythemally weighted to previtamin D3-weighted UV doses". Photochem. Photobiol. 84 (5): 1277–83. doi:10.1111/j. 1751-1097. 2008.00373. x. PMID 18513232. http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0031-8655&date=2008&volume=84&issue=5&spage=1277. 
4. ^ Sayre RM, Dowdy JC (2007). "Darkness at noon: sunscreens and vitamin D3". Photochem. Photobiol. 83 (2): 459–63. doi:10.1562/2006-06-29-RC-956. PMID 17115796. http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0031-8655&date=2007&volume=83&issue=2&spage=459. 
5. ^ Holick, MF (2004). "Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis". The American journal of clinical nutrition 79 (3): 362□71. PMID 14985208. 

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