2017년 2월 20일 월요일

후라비비린

후라비비린

후라비비린
식별자
EC번호 3.4.21.91
CAS 등록 번호 154215-26-6
데이터 베이스
IntEnz IntEnz view
BRENDA(영문판) BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB 구조 RCSB PDB PDBe PDBj PDBsum

후라비비린(Flavivirin, EC 3.4. 21.91)은, 이하의 화학반응을매 하는 효인[1][2][3].

Xaa가 아르기닌 또는 리신, Yaa가 세린 또는 아르기닌이다—Xaa-Xaa-Yaa-결합을 선택적으로 가수분해한다.

이 효소는, 후라비위르스과황열 바이러스, 뎅그열 바이러스에 존재한다.

출전

  1. ^ Chambers, T.J., Hahn, C.S., Galler, R. and Rice, C.M. (1990). "Flavivirus genome organization, expression, and replication". Annu. Rev. Microbiol. 44: 649-688. PMID 2174669. 
  2. ^ Cahour, A., Falgout, B. and Lai, C.-J. (1992). "Cleavage of the dengue virus polyprotein at the NS3/NS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3, whereas NS4A/NS4B may be processed by a cellular protease". J. Virol. 66: 1535-1542. PMID 1531368. 
  3. ^ Lin, C., Amberg, S.M., Chambers, T.J. and Rice, C.M. (1993). "Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4 A/4 B signalase site". J. Virol. 67: 2327-2335. PMID 8445732. 

외부 링크

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